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Expansion of the TLO gene family enhances the virulence of Candida species

The TLO genes are a family of subtelomeric ORFs in the fungal pathogens Candida albicans and C. dubliniensis encoding a subunit of the Mediator complex homologous to Med2. The more virulent pathogen C. albicans has 15 copies of the gene whereas the less pathogenic species C. dubliniensis has only tw...

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Detalles Bibliográficos
Autores principales: Flanagan, Peter R., Fletcher, Jessica, Boyle, Hannah, Sulea, Razvan, Moran, Gary P., Sullivan, Derek J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054389/
https://www.ncbi.nlm.nih.gov/pubmed/30028853
http://dx.doi.org/10.1371/journal.pone.0200852