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nNOS splice variants differentially regulate myofilament function but are dispensable for intracellular calcium and force transients in cardiac papillary muscles

Cardiac muscle expresses three neuronal nitric oxide synthase (nNOS) splice variants: nNOSα, nNOSμ and nNOSβ. The functions of these nNOS splice variants in cardiac muscle, particularly myofilament-associated nNOSβ are unclear. To decipher cardiac nNOS splice variant function we investigated myofila...

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Detalles Bibliográficos
Autores principales: Kerrick, W. Glenn L., Xu, Yuanyuan, Percival, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054407/
https://www.ncbi.nlm.nih.gov/pubmed/30028847
http://dx.doi.org/10.1371/journal.pone.0200834