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Expression and purification of a functional heteromeric GABA(A) receptor for structural studies
The GABA-gated chloride channels of the Cys-loop receptor family, known as GABA(A) receptors, function as the primary gatekeepers of fast inhibitory neurotransmission in the central nervous system. Formed by the pentameric arrangement of five identical or homologous subunits, GABA(A) receptor subtyp...
Autores principales: | Claxton, Derek P., Gouaux, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054424/ https://www.ncbi.nlm.nih.gov/pubmed/30028870 http://dx.doi.org/10.1371/journal.pone.0201210 |
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