Circulating tumor cell-derived organoids: Current challenges and promises in medical research and precision medicine

Traditional 2D cell cultures do not accurately recapitulate tumor heterogeneity, and insufficient human cell lines are available. Patient-derived xenograft (PDX) models more closely mimic clinical tumor heterogeneity, but are not useful for high-throughput drug screening. Recently, patient-derived o...

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Detalles Bibliográficos
Autores principales: Praharaj, Prakash P., Bhutia, Sujit K., Nagrath, Sunitha, Bitting, Rhonda L., Deep, Gagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054479/
https://www.ncbi.nlm.nih.gov/pubmed/29360544
http://dx.doi.org/10.1016/j.bbcan.2017.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054479/
https://www.ncbi.nlm.nih.gov/pubmed/29360544
http://dx.doi.org/10.1016/j.bbcan.2017.12.005

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