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Circulating tumor cell-derived organoids: Current challenges and promises in medical research and precision medicine
Traditional 2D cell cultures do not accurately recapitulate tumor heterogeneity, and insufficient human cell lines are available. Patient-derived xenograft (PDX) models more closely mimic clinical tumor heterogeneity, but are not useful for high-throughput drug screening. Recently, patient-derived o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054479/ https://www.ncbi.nlm.nih.gov/pubmed/29360544 http://dx.doi.org/10.1016/j.bbcan.2017.12.005 |