Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism

Cell proliferation can be dependent on the non-essential amino acid serine, and dietary restriction of serine inhibits tumor growth, but the underlying mechanisms remain incompletely understood. Using a metabolomics approach, we found that serine deprivation most predominantly impacts cellular acylc...

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Detalles Bibliográficos
Autores principales: Gao, Xia, Lee, Katie, Reid, Michael A., Sanderson, Sydney M., Qiu, Chuping, Li, Siqi, Liu, Juan, Locasale, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054483/
https://www.ncbi.nlm.nih.gov/pubmed/29590619
http://dx.doi.org/10.1016/j.celrep.2018.03.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054483/
https://www.ncbi.nlm.nih.gov/pubmed/29590619
http://dx.doi.org/10.1016/j.celrep.2018.03.017

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