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Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism
Cell proliferation can be dependent on the non-essential amino acid serine, and dietary restriction of serine inhibits tumor growth, but the underlying mechanisms remain incompletely understood. Using a metabolomics approach, we found that serine deprivation most predominantly impacts cellular acylc...
Autores principales: | Gao, Xia, Lee, Katie, Reid, Michael A., Sanderson, Sydney M., Qiu, Chuping, Li, Siqi, Liu, Juan, Locasale, Jason W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054483/ https://www.ncbi.nlm.nih.gov/pubmed/29590619 http://dx.doi.org/10.1016/j.celrep.2018.03.017 |
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