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Renal sodium and magnesium reabsorption are not coupled in a mouse model of Gordon syndrome

Active reabsorption of magnesium (Mg(2+)) in the distal convoluted tubule (DCT) of the kidney is crucial for maintaining Mg(2+) homeostasis. Impaired activity of the Na(+)‐Cl(−)‐cotransporter (NCC) has been associated with hypermagnesiuria and hypomagnesemia, while increased activity of NCC, as obse...

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Detalles Bibliográficos
Autores principales: van Megen, Wouter H., Grimm, Paul R., Welling, Paul A., van der Wijst, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054696/
https://www.ncbi.nlm.nih.gov/pubmed/30030908
http://dx.doi.org/10.14814/phy2.13728