A Novel Triple-Mutant AAV6 Capsid Induces Rapid and Potent Transgene Expression in the Muscle and Respiratory Tract of Mice

Gene therapy for the treatment of genetic disorders has demonstrated considerable therapeutic success in clinical trials. Among the most effective and commonly used gene delivery vectors are those based on adeno-associated virus (AAV). Despite these advances in clinical gene therapy, further improve...

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Detalles Bibliográficos
Autores principales: van Lieshout, Laura P., Domm, Jakob M., Rindler, Tara N., Frost, Kathy L., Sorensen, Debra L., Medina, Sarah J., Booth, Stephanie A., Bridges, James P., Wootton, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054702/
https://www.ncbi.nlm.nih.gov/pubmed/30038936
http://dx.doi.org/10.1016/j.omtm.2018.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054702/
https://www.ncbi.nlm.nih.gov/pubmed/30038936
http://dx.doi.org/10.1016/j.omtm.2018.04.005

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