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Dysregulation of human NEFM and NEFH mRNA stability by ALS-linked miRNAs

Neurofilaments (NFs) are the most abundant cytoskeletal component of vertebrate myelinated axons. NFs function by determining axonal caliber, promoting axonal growth and forming a 3-dimensional lattice that supports the organization of cytoplasmic organelles. The stoichiometry of NF protein subunits...

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Detalles Bibliográficos
Autores principales: Campos-Melo, Danae, Hawley, Zachary C. E., Strong, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054723/
https://www.ncbi.nlm.nih.gov/pubmed/30029677
http://dx.doi.org/10.1186/s13041-018-0386-3