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Dysregulation of human NEFM and NEFH mRNA stability by ALS-linked miRNAs
Neurofilaments (NFs) are the most abundant cytoskeletal component of vertebrate myelinated axons. NFs function by determining axonal caliber, promoting axonal growth and forming a 3-dimensional lattice that supports the organization of cytoplasmic organelles. The stoichiometry of NF protein subunits...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054723/ https://www.ncbi.nlm.nih.gov/pubmed/30029677 http://dx.doi.org/10.1186/s13041-018-0386-3 |