The adhesion and migration of microglia to β-amyloid (Aβ) is decreased with aging and inhibited by Nogo/NgR pathway

BACKGROUND: Alzheimer’s disease is characterized by progressive accumulation of β-amyloid (Aβ)-containing amyloid plaques, and microglia play a critical role in internalization and degradation of Aβ. Our previous research confirmed that Nogo-66 binding to Nogo receptors (NgR) expressed on microglia...

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Detalles Bibliográficos
Autores principales: Fang, Yinquan, Wang, Jianing, Yao, Lemeng, Li, Chenhui, Wang, Jing, Liu, Yuan, Tao, Xia, Sun, Hao, Liao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054753/
https://www.ncbi.nlm.nih.gov/pubmed/30029608
http://dx.doi.org/10.1186/s12974-018-1250-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054753/
https://www.ncbi.nlm.nih.gov/pubmed/30029608
http://dx.doi.org/10.1186/s12974-018-1250-1

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