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Novel pharmacological maps of protein lysine methyltransferases: key for target deorphanization
Epigenetic therapies are being investigated for the treatment of cancer, cognitive disorders, metabolic alterations and autoinmune diseases. Among the different epigenetic target families, protein lysine methyltransferases (PKMTs), are especially interesting because it is believed that their inhibit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054832/ https://www.ncbi.nlm.nih.gov/pubmed/30032331 http://dx.doi.org/10.1186/s13321-018-0288-5 |