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Novel pharmacological maps of protein lysine methyltransferases: key for target deorphanization

Epigenetic therapies are being investigated for the treatment of cancer, cognitive disorders, metabolic alterations and autoinmune diseases. Among the different epigenetic target families, protein lysine methyltransferases (PKMTs), are especially interesting because it is believed that their inhibit...

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Detalles Bibliográficos
Autores principales: Rabal, Obdulia, Castellar, Andrea, Oyarzabal, Julen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054832/
https://www.ncbi.nlm.nih.gov/pubmed/30032331
http://dx.doi.org/10.1186/s13321-018-0288-5

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