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Lymphomas driven by Epstein-Barr virus nuclear antigen-1 (EBNA1) are dependant upon Mdm2

Epstein-Barr virus (EBV) associated Burkitt’s lymphoma is characterised by the deregulation of c-Myc expression and a restricted viral gene expression pattern in which the EBV nuclear antigen-1 (EBNA1) is the only viral protein to be consistently expressed. EBNA1 is required for viral genome propaga...

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Detalles Bibliográficos
Autores principales: AlQarni, Sana, Al-Sheikh, Yazeed, Campbell, Donald, Drotar, Mark, Hannigan, Adele, Boyle, Shelagh, Herzyk, Pawel, Kossenkov, Andrew, Armfield, Kate, Jamieson, Lauren, Bailo, Mariarca, Lieberman, Paul M., Tsimbouri, Penelope, Wilson, Joanna B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054874/
https://www.ncbi.nlm.nih.gov/pubmed/29691476
http://dx.doi.org/10.1038/s41388-018-0147-x