Autophagy Differentially Regulates Insulin Production and Insulin Sensitivity

Autophagy, a stress-induced lysosomal degradative pathway, has been assumed to exert similar metabolic effects in different organs. Here, we establish a model where autophagy plays different roles in insulin-producing β cells versus insulin-responsive cells, utilizing knockin (Becn1(F121A)) mice man...

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Detalles Bibliográficos
Autores principales: Yamamoto, Soh, Kuramoto, Kenta, Wang, Nan, Situ, Xiaolei, Priyadarshini, Medha, Zhang, Weiran, Cordoba-Chacon, Jose, Layden, Brian T., He, Congcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054876/
https://www.ncbi.nlm.nih.gov/pubmed/29898399
http://dx.doi.org/10.1016/j.celrep.2018.05.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054876/
https://www.ncbi.nlm.nih.gov/pubmed/29898399
http://dx.doi.org/10.1016/j.celrep.2018.05.032

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