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Autophagy Differentially Regulates Insulin Production and Insulin Sensitivity
Autophagy, a stress-induced lysosomal degradative pathway, has been assumed to exert similar metabolic effects in different organs. Here, we establish a model where autophagy plays different roles in insulin-producing β cells versus insulin-responsive cells, utilizing knockin (Becn1(F121A)) mice man...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054876/ https://www.ncbi.nlm.nih.gov/pubmed/29898399 http://dx.doi.org/10.1016/j.celrep.2018.05.032 |