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Vitamin K Deficiency Induced by Warfarin Is Associated With Cognitive and Behavioral Perturbations, and Alterations in Brain Sphingolipids in Rats

Initially discovered for its role in blood coagulation, there is now convincing evidence that vitamin K (VK) has important actions in the nervous system. In brain, VK is present in the form of menaquinone-4 (MK-4), a byproduct of the main dietary source, phylloquinone. It contributes to the biologic...

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Detalles Bibliográficos
Autores principales: Tamadon-Nejad, Sahar, Ouliass, Bouchra, Rochford, Joseph, Ferland, Guylaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054920/
https://www.ncbi.nlm.nih.gov/pubmed/30061825
http://dx.doi.org/10.3389/fnagi.2018.00213