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TRPA1 sensitization during diabetic vascular impairment contributes to cold hypersensitivity in a mouse model of painful diabetic peripheral neuropathy

BACKGROUND: Diabetic peripheral neuropathy is a common long-term complication of diabetes. Accumulating evidence suggests that vascular impairment plays important roles in the pathogenesis of diabetic peripheral neuropathy, while the mechanism remains unclear. We recently reported that transient rec...

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Detalles Bibliográficos
Autores principales: Hiyama, Haruka, Yano, Yuichi, So, Kanako, Imai, Satoshi, Nagayasu, Kazuki, Shirakawa, Hisashi, Nakagawa, Takayuki, Kaneko, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055098/
https://www.ncbi.nlm.nih.gov/pubmed/29968518
http://dx.doi.org/10.1177/1744806918789812