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A Fully Automated High-Throughput Flow Cytometry Screening System Enabling Phenotypic Drug Discovery

The goal of high-throughput screening is to enable screening of compound libraries in an automated manner to identify quality starting points for optimization. This often involves screening a large diversity of compounds in an assay that preserves a connection to the disease pathology. Phenotypic sc...

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Detalles Bibliográficos
Autores principales: Joslin, John, Gilligan, James, Anderson, Paul, Garcia, Catherine, Sharif, Orzala, Hampton, Janice, Cohen, Steven, King, Miranda, Zhou, Bin, Jiang, Shumei, Trussell, Christopher, Dunn, Robert, Fathman, John W., Snead, Jennifer L., Boitano, Anthony E., Nguyen, Tommy, Conner, Michael, Cooke, Mike, Harris, Jennifer, Ainscow, Ed, Zhou, Yingyao, Shaw, Chris, Sipes, Dan, Mainquist, James, Lesley, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055113/
https://www.ncbi.nlm.nih.gov/pubmed/29843542
http://dx.doi.org/10.1177/2472555218773086