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Distribution shapes govern the discovery of predictive models for gene regulation

Despite substantial experimental and computational efforts, mechanistic modeling remains more predictive in engineering than in systems biology. The reason for this discrepancy is not fully understood. One might argue that the randomness and complexity of biological systems are the main barriers to...

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Detalles Bibliográficos
Autores principales: Munsky, Brian, Li, Guoliang, Fox, Zachary R., Shepherd, Douglas P., Neuert, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055173/
https://www.ncbi.nlm.nih.gov/pubmed/29959206
http://dx.doi.org/10.1073/pnas.1804060115