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Distinct ways of G:U recognition by conserved tRNA binding motifs

Throughout three domains of life, alanyl-tRNA synthetases (AlaRSs) recognize a G3:U70 base pair in the acceptor stem of tRNA(Ala) as the major identity determinant of tRNA(Ala). The crystal structure of the archaeon Archaeoglobus fulgidus AlaRS in complex with tRNA(Ala) provided the basis for G3:U70...

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Detalles Bibliográficos
Autores principales: Chong, Yeeting E., Guo, Min, Yang, Xiang-Lei, Kuhle, Bernhard, Naganuma, Masahiro, Sekine, Shun-ichi, Yokoyama, Shigeyuki, Schimmel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055181/
https://www.ncbi.nlm.nih.gov/pubmed/29967150
http://dx.doi.org/10.1073/pnas.1807109115