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Distinct ways of G:U recognition by conserved tRNA binding motifs
Throughout three domains of life, alanyl-tRNA synthetases (AlaRSs) recognize a G3:U70 base pair in the acceptor stem of tRNA(Ala) as the major identity determinant of tRNA(Ala). The crystal structure of the archaeon Archaeoglobus fulgidus AlaRS in complex with tRNA(Ala) provided the basis for G3:U70...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055181/ https://www.ncbi.nlm.nih.gov/pubmed/29967150 http://dx.doi.org/10.1073/pnas.1807109115 |