Hypoxia inducible factor 2α (HIF2α/EPAS1) is associated with development of pulmonary hypertension in severe congenital diaphragmatic hernia patients

We show that hypoxia inducible factor 2α (HIF2α) is highly expressed in patients with pulmonary hypertension (PH). HIF2α is expressed in every patient with congenital diaphragmatic hernia, while only half of the controls express HIF2α. Our data suggest that HIF2α is a link between hypoxia and the de...

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Detalles Bibliográficos
Autores principales: Huang, Yadi, Boerema-de Munck, Anne, Buscop-van Kempen, Marjon, Sluiter, Ilona, de Krijger, Ronald, Tibboel, Dick, Rottier, Robbert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055252/
https://www.ncbi.nlm.nih.gov/pubmed/29855254
http://dx.doi.org/10.1177/2045894018783734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055252/
https://www.ncbi.nlm.nih.gov/pubmed/29855254
http://dx.doi.org/10.1177/2045894018783734

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