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JNK2 regulates vascular remodeling in pulmonary hypertension

Pulmonary arterial (PA) wall modifications are key pathological features of pulmonary hypertension (PH). Although such abnormalities correlate with heightened phosphorylation of c-Jun N-terminal kinases 1/2 (JNK1/2) in a rat model of PH, the contribution of specific JNK isoforms to the pathophysiolo...

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Detalles Bibliográficos
Autores principales: Das, Mita, Zawada, W. Michael, West, James, Stenmark, Kurt R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055330/
https://www.ncbi.nlm.nih.gov/pubmed/29718758
http://dx.doi.org/10.1177/2045894018778156