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Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy
Tau is normally a highly soluble phosphoprotein found predominantly in neurons. Six different isoforms of tau are expressed in the adult human CNS. Under pathological conditions, phosphorylated tau aggregates are a defining feature of neurodegenerative disorders called tauopathies. Recent findings h...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055332/ https://www.ncbi.nlm.nih.gov/pubmed/30037345 http://dx.doi.org/10.1186/s40478-018-0568-3 |