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Optic nerve as a source of activated retinal microglia post-injury

Using mice expressing green fluorescent protein (GFP) from a transgenic CD11c promoter we found that a controlled optic nerve crush (ONC) injury attracted GFP(hi) retinal myeloid cells to the dying retinal ganglion cells and their axons. However, the origin of these retinal myeloid cells was uncerta...

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Detalles Bibliográficos
Autores principales: Heuss, Neal D., Pierson, Mark J., Roehrich, Heidi, McPherson, Scott W., Gram, Andrea L., Li, Ling, Gregerson, Dale S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055350/
https://www.ncbi.nlm.nih.gov/pubmed/30037353
http://dx.doi.org/10.1186/s40478-018-0571-8