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Optic nerve as a source of activated retinal microglia post-injury
Using mice expressing green fluorescent protein (GFP) from a transgenic CD11c promoter we found that a controlled optic nerve crush (ONC) injury attracted GFP(hi) retinal myeloid cells to the dying retinal ganglion cells and their axons. However, the origin of these retinal myeloid cells was uncerta...
Autores principales: | Heuss, Neal D., Pierson, Mark J., Roehrich, Heidi, McPherson, Scott W., Gram, Andrea L., Li, Ling, Gregerson, Dale S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055350/ https://www.ncbi.nlm.nih.gov/pubmed/30037353 http://dx.doi.org/10.1186/s40478-018-0571-8 |
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