Cargando…

Human Bone Marrow-Derived Myeloid Dendritic Cells Show an Immature Transcriptional and Functional Profile Compared to Their Peripheral Blood Counterparts and Separate from Slan+ Non-Classical Monocytes

The human bone marrow (BM) gives rise to all distinct blood cell lineages, including CD1c+ (cDC2) and CD141+ (cDC1) myeloid dendritic cells (DC) and monocytes. These cell subsets are also present in peripheral blood (PB) and lymphoid tissues. However, the difference between the BM and PB compartment...

Descripción completa

Detalles Bibliográficos
Autores principales: van Leeuwen-Kerkhoff, Nathalie, Lundberg, Kristina, Westers, Theresia M., Kordasti, Shahram, Bontkes, Hetty J., Lindstedt, Malin, de Gruijl, Tanja D., van de Loosdrecht, Arjan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055354/
https://www.ncbi.nlm.nih.gov/pubmed/30061890
http://dx.doi.org/10.3389/fimmu.2018.01619