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Design and rationale for the DIVERSITY study: An open‐label, randomized study of dabigatran etexilate for pediatric venous thromboembolism

ESSENTIALS: Current standard of care (SOC) for pediatric venous thromboembolism (VTE) has limitations. Dabigatran etexilate (DE) versus SOC will be studied in children with VTE in a phase IIb/III trial. A dosing algorithm for DE in children will be assessed guiding dosing. Valuable data on the safet...

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Detalles Bibliográficos
Autores principales: Albisetti, Manuela, Biss, Branislav, Bomgaars, Lisa, Brandão, Leonardo R., Brueckmann, Martina, Chalmers, Elizabeth, Gropper, Savion, Harper, Ruth, Huang, Fenglei, Luciani, Matteo, Manastirski, Ivan, Mitchell, Lesley G., Tartakovsky, Igor, Wang, Bushi, Halton, Jacqueline M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055566/
https://www.ncbi.nlm.nih.gov/pubmed/30046738
http://dx.doi.org/10.1002/rth2.12086