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Factor V‐short and protein S as synergistic tissue factor pathway inhibitor (TFPIα) cofactors
ESSENTIALS: FV‐Short, a normal splice isoform of Factor V, binds tissue factor pathway inhibitor (TFPIα) with high affinity. FV‐Short functions as a synergistic TFPIα cofactor with protein S in inhibition of Factor Xa. FV‐Short is much more efficient as TFPIα cofactor than full length FV. TFPIα‐cofa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055574/ https://www.ncbi.nlm.nih.gov/pubmed/30046712 http://dx.doi.org/10.1002/rth2.12057 |