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Factor V‐short and protein S as synergistic tissue factor pathway inhibitor (TFPIα) cofactors

ESSENTIALS: FV‐Short, a normal splice isoform of Factor V, binds tissue factor pathway inhibitor (TFPIα) with high affinity. FV‐Short functions as a synergistic TFPIα cofactor with protein S in inhibition of Factor Xa. FV‐Short is much more efficient as TFPIα cofactor than full length FV. TFPIα‐cofa...

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Detalles Bibliográficos
Autores principales:	Dahlbäck, Björn, Guo, Li Jun, Livaja‐Koshiar, Ruzica, Tran, Sinh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles: Haemostasis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055574/ https://www.ncbi.nlm.nih.gov/pubmed/30046712 http://dx.doi.org/10.1002/rth2.12057

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