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Conformationally Programmable Chiral Foldamers with Compact and Extended Domains Controlled by Monomer Structure
Foldamers are an important class of abiotic macromolecules, with potential therapeutic applications in the disruption of protein–protein interactions. The majority adopt a single conformational motif such as a helix. A class of foldamer is now introduced where the choice of heterocycle within each m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055681/ https://www.ncbi.nlm.nih.gov/pubmed/29737622 http://dx.doi.org/10.1002/anie.201802822 |