Running on mixed fuel‐dual agonistic approach of GLP‐1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non‐human primates

AIM: We performed acute and chronic studies in healthy and diet‐induced obese animals using mouse‐specific or monkey‐specific dual GLP‐1R/GCGR agonists to investigate their effects on food intake, body weight, blood glucose control and insulin secretion. The selective GLP‐1R agonist liraglutide was...

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Detalles Bibliográficos
Autores principales: Elvert, Ralf, Herling, Andreas W., Bossart, Martin, Weiss, Tilo, Zhang, Baohong, Wenski, Pierre, Wandschneider, Jörn, Kleutsch, Sabrina, Butty, Uwe, Kannt, Aimo, Wagner, Michael, Haack, Torsten, Evers, Andreas, Dudda, Angela, Lorenz, Martin, Keil, Stefanie, Larsen, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055720/
https://www.ncbi.nlm.nih.gov/pubmed/29938884
http://dx.doi.org/10.1111/dom.13212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055720/
https://www.ncbi.nlm.nih.gov/pubmed/29938884
http://dx.doi.org/10.1111/dom.13212

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