The effect of FASN inhibition on the growth and metabolism of a cisplatin‐resistant ovarian carcinoma model

Overexpression of fatty acid synthase (FASN), a key regulator of the de novo synthesis of fatty acids, has been demonstrated in a variety of cancers and is associated with poor prognosis and increased multidrug resistance. Inhibition of FASN with the anti‐obesity drug orlistat has been shown to have...

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Detalles Bibliográficos
Autores principales: Papaevangelou, Efthymia, Almeida, Gilberto S., Box, Carol, deSouza, Nandita M., Chung, Yuen‐Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Therapy and Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055739/
https://www.ncbi.nlm.nih.gov/pubmed/29569717
http://dx.doi.org/10.1002/ijc.31392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055739/
https://www.ncbi.nlm.nih.gov/pubmed/29569717
http://dx.doi.org/10.1002/ijc.31392

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