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The effect of FASN inhibition on the growth and metabolism of a cisplatin‐resistant ovarian carcinoma model

Overexpression of fatty acid synthase (FASN), a key regulator of the de novo synthesis of fatty acids, has been demonstrated in a variety of cancers and is associated with poor prognosis and increased multidrug resistance. Inhibition of FASN with the anti‐obesity drug orlistat has been shown to have...

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Detalles Bibliográficos
Autores principales:	Papaevangelou, Efthymia, Almeida, Gilberto S., Box, Carol, deSouza, Nandita M., Chung, Yuen‐Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Cancer Therapy and Prevention
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055739/ https://www.ncbi.nlm.nih.gov/pubmed/29569717 http://dx.doi.org/10.1002/ijc.31392

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