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Basolateral CD147 induces hepatocyte polarity loss by E‐cadherin ubiquitination and degradation in hepatocellular carcinoma progress

Hepatocytes are epithelial cells with highly specialized polarity. The disorder and loss of hepatocyte polarity leads to a weakness of cell adhesion and connection, the induction of epithelial–mesenchymal transition, and eventually the occurrence of hepatocellular carcinoma (HCC). Cluster of differe...

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Detalles Bibliográficos
Autores principales: Lu, Meng, Wu, Jiao, Hao, Zhi‐Wei, Shang, Yu‐Kui, Xu, Jing, Nan, Gang, Li, Xia, Chen, Zhi‐Nan, Bian, Huijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055794/
https://www.ncbi.nlm.nih.gov/pubmed/29356040
http://dx.doi.org/10.1002/hep.29798