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Basolateral CD147 induces hepatocyte polarity loss by E‐cadherin ubiquitination and degradation in hepatocellular carcinoma progress
Hepatocytes are epithelial cells with highly specialized polarity. The disorder and loss of hepatocyte polarity leads to a weakness of cell adhesion and connection, the induction of epithelial–mesenchymal transition, and eventually the occurrence of hepatocellular carcinoma (HCC). Cluster of differe...
Autores principales: | Lu, Meng, Wu, Jiao, Hao, Zhi‐Wei, Shang, Yu‐Kui, Xu, Jing, Nan, Gang, Li, Xia, Chen, Zhi‐Nan, Bian, Huijie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055794/ https://www.ncbi.nlm.nih.gov/pubmed/29356040 http://dx.doi.org/10.1002/hep.29798 |
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