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Super analgesia of intrathecal morphine may be related to ABCB1 (MDR1) gene polymorphism
Intrathecal morphine provides superior analgesia and minimizes side effects with ~1/300th of the oral dose necessary to achieve this effect. The conversion ratios from oral route to intrathecal route vary greatly among individuals, and this may be related with polymorphisms of the ATP-binding casset...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055837/ https://www.ncbi.nlm.nih.gov/pubmed/30050319 http://dx.doi.org/10.2147/JPR.S156919 |