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Super analgesia of intrathecal morphine may be related to ABCB1 (MDR1) gene polymorphism

Intrathecal morphine provides superior analgesia and minimizes side effects with ~1/300th of the oral dose necessary to achieve this effect. The conversion ratios from oral route to intrathecal route vary greatly among individuals, and this may be related with polymorphisms of the ATP-binding casset...

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Detalles Bibliográficos
Autores principales:	Qin, Wangjun, Liu, Botao, Deng, Ang, Liu, Ying, Zhang, Xianglin, Zhang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055837/ https://www.ncbi.nlm.nih.gov/pubmed/30050319 http://dx.doi.org/10.2147/JPR.S156919

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