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Tailored Mutants of Phenylalanine Ammonia‐Lyase from Petroselinum crispum for the Synthesis of Bulky l‐ and d‐Arylalanines

Tailored mutants of phenylalanine ammonia‐lyase from Petroselinum crispum (PcPAL) were created and tested in ammonia elimination from various sterically demanding, non‐natural analogues of phenylalanine and in ammonia addition reactions into the corresponding (E)‐arylacrylates. The wild‐type PcPAL w...

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Detalles Bibliográficos
Autores principales: Filip, Alina, Nagy, Emma Z. A., Tork, Souad D., Bánóczi, Gergely, Toşa, Monica I., Irimie, Florin D., Poppe, László, Paizs, Csaba, Bencze, László C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055856/
https://www.ncbi.nlm.nih.gov/pubmed/30069247
http://dx.doi.org/10.1002/cctc.201800258