Cargando…

Tailored Mutants of Phenylalanine Ammonia‐Lyase from Petroselinum crispum for the Synthesis of Bulky l‐ and d‐Arylalanines

Tailored mutants of phenylalanine ammonia‐lyase from Petroselinum crispum (PcPAL) were created and tested in ammonia elimination from various sterically demanding, non‐natural analogues of phenylalanine and in ammonia addition reactions into the corresponding (E)‐arylacrylates. The wild‐type PcPAL w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Filip, Alina, Nagy, Emma Z. A., Tork, Souad D., Bánóczi, Gergely, Toşa, Monica I., Irimie, Florin D., Poppe, László, Paizs, Csaba, Bencze, László C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055856/ https://www.ncbi.nlm.nih.gov/pubmed/30069247 http://dx.doi.org/10.1002/cctc.201800258

Ejemplares similares

The production of l- and d-phenylalanines using engineered phenylalanine ammonia lyases from Petroselinum crispum
por: Tork, Souad Diana, et al.
Publicado: (2019)

Expression and Properties of the Highly Alkalophilic Phenylalanine Ammonia-Lyase of Thermophilic Rubrobacter xylanophilus
por: Kovács, Klaudia, et al.
Publicado: (2014)

Immobilization of Phenylalanine Ammonia‐Lyase on Single‐Walled Carbon Nanotubes for Stereoselective Biotransformations in Batch and Continuous‐Flow Modes
por: Bartha‐Vári, Judith H., et al.
Publicado: (2015)

Towards a general approach for tailoring the hydrophobic binding site of phenylalanine ammonia-lyases
por: Tork, Souad Diana, et al.
Publicado: (2022)

Robust, site-specifically immobilized phenylalanine ammonia-lyases for the enantioselective ammonia addition of cinnamic acids
por: Boros, Krisztina, et al.
Publicado: (2021)

Fluorescent enzyme-coupled activity assay for phenylalanine ammonia-lyases
por: Moisă, Mădălina E., et al.
Publicado: (2020)

A Methylidene Group in the Phosphonic Acid Analogue of Phenylalanine Reverses the Enantiopreference of Binding to Phenylalanine Ammonia‐Lyases
por: Bata, Zsófia, et al.
Publicado: (2017)

Saturation Mutagenesis for Phenylalanine Ammonia Lyases of Enhanced Catalytic Properties
por: Tomoiagă, Raluca Bianca, et al.
Publicado: (2020)

“Fishing and Hunting”—Selective Immobilization of a Recombinant Phenylalanine Ammonia-Lyase from Fermentation Media
por: Sánta-Bell, Evelin, et al.
Publicado: (2019)

Improvement of Petroselinum crispum on Morphine Toxicity in Prefrontal Cortex in Rats
por: Salahshoor, Mohammad Reza, et al.
Publicado: (2020)

Features of Copper and Gold Nanoparticle Translocation in Petroselinum crispum Segments
por: Peshkova, Alexandra, et al.
Publicado: (2023)

Petroselinum Crispum is Effective in Reducing Stress-Induced Gastric Oxidative Damage
por: Akıncı, Ayşin, et al.
Publicado: (2017)

Fungal and Plant Phenylalanine Ammonia-lyase
por: Hyun, Min Woo, et al.
Publicado: (2011)

Biochemical Changes in Two Parsley (Petroselinum crispum L.) Varieties during Saline Stress
por: OPRICĂ, Lăcrămioara, et al.
Publicado: (2014)

Heterocycles 36. Single-Walled Carbon Nanotubes-Bound N,N-Diethyl Ethanolamine as Mild and Efficient Racemisation Agent in the Enzymatic DKR of 2-Arylthiazol-4-yl-alanines
por: Leonte, Denisa, et al.
Publicado: (2015)

Molecular and Histopathological Study on the Ameliorative Impacts of Petroselinum Crispum and Apium Graveolens against Experimental Hyperuricemia
por: Soliman, Mohamed Mohamed, et al.
Publicado: (2020)

Genomic Characterization of Phenylalanine Ammonia Lyase Gene in Buckwheat
por: Thiyagarajan, Karthikeyan, et al.
Publicado: (2016)

Efficient and Stable Magnetic Chitosan-Lipase B from Candida Antarctica Bioconjugates in the Enzymatic Kinetic Resolution of Racemic Heteroarylethanols
por: Spelmezan, Cristina Georgiana, et al.
Publicado: (2020)

Evaluation of the antibacterial potential of Petroselinum crispum and Rosmarinus officinalis against bacteria that cause urinary tract infections
por: Petrolini, Fernanda Villas Boas, et al.
Publicado: (2013)

Effect of parsley (Petroselinum crispum, Apiaceae) juice against cadmium neurotoxicity in albino mice (Mus Musculus)
por: Maodaa, Saleh N., et al.
Publicado: (2016)

Antiosteoporotic effect of Petroselinum crispum, Ocimum basilicum and Cichorium intybus L. in glucocorticoid-induced osteoporosis in rats
por: Hozayen, Walaa G., et al.
Publicado: (2016)

Protective effect of Petroselinum crispum extract in abortion using prostadin-induced renal dysfunction in female rats
por: Rezazad, Maryam, et al.
Publicado: (2014)

Roots of Apium graveolens and Petroselinum crispum—Insight into Phenolic Status against Toxicity Level of Trace Elements
por: Arsenov, Danijela, et al.
Publicado: (2021)

Efficiency of Coriandrum sativum (Linn.) and Petroselinum crispum (Mill.) in Enhancing Iron Absorption: An In Silico and In Vitro Approach
por: Sangeetha, T., et al.
Publicado: (2022)

Purification and Characterization of Phenylalanine Ammonia Lyase from Trichosporon cutaneum
por: Goldson-Barnaby, Andrea, et al.
Publicado: (2013)

Efficient Biodiesel Production Catalyzed by Nanobioconjugate of Lipase from Pseudomonas fluorescens
por: Bartha-Vári, Judith-Hajnal, et al.
Publicado: (2020)

Synthesis of d- and l-Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process**
por: Parmeggiani, Fabio, et al.
Publicado: (2015)

Synthesis of d‐ and l‐Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process
por: Parmeggiani, Fabio, et al.
Publicado: (2015)

Petroselinum crispum has antioxidant properties, protects against DNA damage and inhibits proliferation and migration of cancer cells
por: Tang, Esther Lai‐Har, et al.
Publicado: (2015)

Suitable Reference Genes for Accurate Gene Expression Analysis in Parsley (Petroselinum crispum) for Abiotic Stresses and Hormone Stimuli
por: Li, Meng-Yao, et al.
Publicado: (2016)

Biochemical Effects of Petroselinum crispum (Umbellifereae) Essential Oil on the Pyrethroid Resistant Strains of Aedes aegypti (Diptera: Culicidae)
por: Intirach, Jitrawadee, et al.
Publicado: (2018)

Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes
por: Weise, Nicholas J., et al.
Publicado: (2017)

Antioxidant Potential of Parsley Leaf (Petroselinum crispum) Essential Oil on Hypothyroidism and Testicular Injury in Mice Intoxicated by Carbon Tetrachloride
por: Badr, Gehan M., et al.
Publicado: (2021)

Phytochemical Screening, In Vitro and In Silico Studies of Volatile Compounds from Petroselinum crispum (Mill) Leaves Grown in Saudi Arabia
por: Foudah, Ahmed I., et al.
Publicado: (2022)

Immobilization of Cross-Linked Phenylalanine Ammonia Lyase Aggregates in Microporous Silica Gel
por: Cui, Jian Dong, et al.
Publicado: (2013)

Formulation and PEGylation optimization of the therapeutic PEGylated phenylalanine ammonia lyase for the treatment of phenylketonuria
por: Bell, Sean M., et al.
Publicado: (2017)

Functional and kinetics of two efficient phenylalanine ammonia lyase from Pyrus bretschneideri
por: Li, Guohui, et al.
Publicado: (2023)

Petroselinum crispum, a commonly consumed food, affects sirolimus level in a renal transplant recipient: a case report
por: Kurtaran, Melek, et al.
Publicado: (2021)

Heterocycles 38. Biocatalytic Synthesis of New Heterocyclic Mannich Bases and Derivatives
por: Leonte, Denisa, et al.
Publicado: (2015)

Study of the l-Phenylalanine Ammonia-Lyase Penetration Kinetics and the Efficacy of Phenylalanine Catabolism Correction Using In Vitro Model Systems
por: Dyshlyuk, Lyubov, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ubsp9aoea4latl3ne31n5lk7s3