Media photo‐degradation in pharmaceutical biotechnology – impact of ambient light on media quality, cell physiology, and IgG production in CHO cultures

BACKGROUND: Many vital components in bioprocess media are prone to photo‐conversion or photo‐degradation upon exposure to ambient light, with severe negative consequences for biomass yield and overall productivity. However, there is only limited awareness of light irradiation as a potential risk fac...

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Detalles Bibliográficos
Autores principales: Neutsch, Lukas, Kroll, Paul, Brunner, Matthias, Pansy, Alexander, Kovar, Michael, Herwig, Christoph, Klein, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055871/
https://www.ncbi.nlm.nih.gov/pubmed/30069078
http://dx.doi.org/10.1002/jctb.5643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055871/
https://www.ncbi.nlm.nih.gov/pubmed/30069078
http://dx.doi.org/10.1002/jctb.5643

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