Spiro‐epoxyglycosides as Activity‐Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase

N‐Glycans direct protein function, stability, folding and targeting, and influence immunogenicity. While most glycosidases that process N‐glycans cleave a single sugar residue at a time, enzymes from glycoside hydrolase family 99 are endo‐acting enzymes that cleave within complex N‐glycans. Eukaryot...

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Detalles Bibliográficos
Autores principales: Schröder, Sybrin P., Kallemeijn, Wouter W., Debets, Marjoke F., Hansen, Thomas, Sobala, Lukasz F., Hakki, Zalihe, Williams, Spencer J., Beenakker, Thomas J. M., Aerts, Johannes M. F. G., van der Marel, Gijsbert A., Codée, Jeroen D. C., Davies, Gideon J., Overkleeft, Herman S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055899/
https://www.ncbi.nlm.nih.gov/pubmed/29797675
http://dx.doi.org/10.1002/chem.201801902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055899/
https://www.ncbi.nlm.nih.gov/pubmed/29797675
http://dx.doi.org/10.1002/chem.201801902

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