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Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation

Understanding the mechanisms governing innovation is a central element of evolutionary theory. Novel traits usually arise through mutations in existing genes, but trade-offs between new and ancestral protein functions are pervasive and constrain the evolution of innovation. Classical models posit th...

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Detalles Bibliográficos
Autores principales: Rodriguez-Beltran, Jeronimo, Hernandez-Beltran, J. Carlos R., DelaFuente, Javier, Escudero, Jose A., Fuentes-Hernandez, Ayari, MacLean, R. Craig, Peña-Miller, Rafael, San Millan, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055991/
https://www.ncbi.nlm.nih.gov/pubmed/29632354
http://dx.doi.org/10.1038/s41559-018-0529-z