Role of Bicaudal C1 in renal gluconeogenesis and its novel interaction with the CTLH complex

Altered glucose and lipid metabolism fuel cystic growth in polycystic kidneys, but the cause of these perturbations is unclear. Renal cysts also associate with mutations in Bicaudal C1 (Bicc1) or in its self-polymerizing sterile alpha motif (SAM). Here, we found that Bicc1 maintains normoglycemia an...

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Detalles Bibliográficos
Autores principales: Leal-Esteban, Lucia Carolina, Rothé, Benjamin, Fortier, Simon, Isenschmid, Manuela, Constam, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056059/
https://www.ncbi.nlm.nih.gov/pubmed/29995892
http://dx.doi.org/10.1371/journal.pgen.1007487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056059/
https://www.ncbi.nlm.nih.gov/pubmed/29995892
http://dx.doi.org/10.1371/journal.pgen.1007487

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