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Selected HLA-B allotypes are resistant to inhibition or deficiency of the transporter associated with antigen processing (TAP)

Major histocompatibility complex class I (MHC-I) molecules present antigenic peptides to CD8(+) T cells, and are also important for natural killer (NK) cell immune surveillance against infections and cancers. MHC-I molecules are assembled via a complex assembly pathway in the endoplasmic reticulum (...

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Detalles Bibliográficos
Autores principales: Geng, Jie, Zaitouna, Anita J., Raghavan, Malini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056074/
https://www.ncbi.nlm.nih.gov/pubmed/29995954
http://dx.doi.org/10.1371/journal.ppat.1007171