Inhibition of MUC1-C entering nuclear suppresses MYC expression and attenuates malignant growth in esophageal squamous cell carcinoma

BACKGROUND: The mucin 1 (MUC1) heterodimeric protein (N-terminal subunit and C-terminal subunit) is aberrantly overexpressed in esophageal squamous cell carcinoma (ESCC) and has been linked to poor outcomes in this disease. The detailed mechanism(s), however, remains unclear. In this article, we inv...

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Detalles Bibliográficos
Autores principales: Xin, Zhongwei, Xin, Gongsun, Shi, Mo, Song, Liang, Wang, Qiang, Jiang, Bin, Liu, Xiangyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056156/
https://www.ncbi.nlm.nih.gov/pubmed/30050304
http://dx.doi.org/10.2147/OTT.S168813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056156/
https://www.ncbi.nlm.nih.gov/pubmed/30050304
http://dx.doi.org/10.2147/OTT.S168813

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