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Human demographic history has amplified the effects of background selection across the genome

Natural populations often grow, shrink, and migrate over time. Such demographic processes can affect genome-wide levels of genetic diversity. Additionally, genetic variation in functional regions of the genome can be altered by natural selection, which drives adaptive mutations to higher frequencies...

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Detalles Bibliográficos
Autores principales: Torres, Raul, Szpiech, Zachary A., Hernandez, Ryan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056204/
https://www.ncbi.nlm.nih.gov/pubmed/29912945
http://dx.doi.org/10.1371/journal.pgen.1007387