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Human demographic history has amplified the effects of background selection across the genome
Natural populations often grow, shrink, and migrate over time. Such demographic processes can affect genome-wide levels of genetic diversity. Additionally, genetic variation in functional regions of the genome can be altered by natural selection, which drives adaptive mutations to higher frequencies...
Autores principales: | Torres, Raul, Szpiech, Zachary A., Hernandez, Ryan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056204/ https://www.ncbi.nlm.nih.gov/pubmed/29912945 http://dx.doi.org/10.1371/journal.pgen.1007387 |
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