Cargando…

RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs

Polarised mRNA transport is a prevalent mechanism for spatial control of protein synthesis. However, the composition of transported ribonucleoprotein particles (RNPs) and the regulation of their movement are poorly understood. We have reconstituted microtubule minus end-directed transport of mRNAs u...

Descripción completa

Detalles Bibliográficos
Autores principales: McClintock, Mark A, Dix, Carly I, Johnson, Christopher M, McLaughlin, Stephen H, Maizels, Rory J, Hoang, Ha Thi, Bullock, Simon L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056234/
https://www.ncbi.nlm.nih.gov/pubmed/29944118
http://dx.doi.org/10.7554/eLife.36312