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Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complex

We investigated the role of full-length Drosophila Bicaudal D (BicD) binding partners in dynein-dynactin activation for mRNA transport on microtubules. Full-length BicD robustly activated dynein-dynactin motility only when both the mRNA binding protein Egalitarian (Egl) and K10 mRNA cargo were prese...

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Detalles Bibliográficos
Autores principales: Sladewski, Thomas E, Billington, Neil, Ali, M Yusuf, Bookwalter, Carol S, Lu, Hailong, Krementsova, Elena B, Schroer, Trina A, Trybus, Kathleen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056235/
https://www.ncbi.nlm.nih.gov/pubmed/29944116
http://dx.doi.org/10.7554/eLife.36306